Two New Bioactive Biphenylpropanoids from the Roots of Salsola imbricata (Chenopodiaceae) Growing in Saudi Arabia
نویسندگان
چکیده
Phytochemical investigation of the roots of Salsola imbricata allowed to two new bioactive biphenylpropanoids (1) and (2) named, biphenylsalsonoid A and B, respectively. Their structures were established through spectroscopic methods (1D and 2D NMR, (ES)-HRMS, and IR). The isolates were tested for their antioxidant activity using DPPH• and ABTS•+ assays. 1 and 2 showed a moderate activity towards DPPH (IC50 = 86.5 ± 1.3 and 122.3 ± 0.63 mg/mL, respectively) and ABTS (IC50 = 95 ± 1.5, 137.7 ± 1.2 mg/mL, respectively). The antibacterial effect of the ethyl acetate extract and the isolates were assessed. Results obtained revealed that compounds showed important antibacterial activities against S. aureus, S. epidermidis, M. luteus, and E. coli with MIC values ranging from 16 to 32 mg/mL.
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